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The main objectives were to compare the efficacy of extracts of the plant Tribulus terrestris (TT; marketed as Tribestan), in contrast with placebo, for the treatment of guys with impotence (ED) and with or without hypoactive sexual desire condition (HSDD), along with to keep track of the security profile of the drug.

Phase IV, potential, randomized, double-blind, placebo-controlled clinical trial in parallel groups. This study consisted of 180 males aged in between 18 and 65 years with mild or moderate ED and with or without HSDD: 90 were randomized to TT and 90 to placebo. tribestan with ED and high blood pressure, diabetes mellitus, and metabolic syndrome were consisted of in the study.

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Each Tribestan film-coated tablet contains the active compound Tribulus terrestris, herba extractum siccum (35-45:1) 250mg which is standardized to furostanol saponins (not less than 112. 5mg). Each client received orally 32 film-coated tablets daily after meals, throughout the 12-week treatment duration. At the end of every month, participants' sexual function, consisting of ED, was assessed by International Index of Erectile Function (IIEF) Questionnaire and Worldwide Efficacy Concern (GEQ).

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The primary result procedure was the change in IIEF rating after 12 weeks of treatment. Complete randomization (random sorting utilizing maximum allowable% deviation) with an equal variety of patients in each sequence was used. This randomization algorithm has the restriction that unequal treatment allowance is not allowed; that is, all groups must have the very same target sample size.

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All result assessors were likewise blinded to group allotment. 86 patients in each group completed the research study. The IIEF score improved significantly in the TT group compared to the placebo group (