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The primary objectives were to compare the efficacy of extracts of the plant Tribulus terrestris (TT; marketed as Tribestan), in comparison with placebo, for the treatment of men with impotence (ED) and with or without hypoactive libido disorder (HSDD), in addition to to keep an eye on the safety profile of the drug.

Stage IV, potential, randomized, double-blind, placebo-controlled medical trial in parallel groups. This research study consisted of 180 males aged in between 18 and 65 years with moderate or moderate ED and with or without HSDD: 90 were randomized to TT and 90 to placebo. tribestan 250mg with ED and high blood pressure, diabetes mellitus, and metabolic syndrome were consisted of in the study.

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Each Tribestan film-coated tablet consists of the active compound Tribulus terrestris, herba extractum siccum (35-45:1) 250mg which is standardized to furostanol saponins (not less than 112. 5mg). Each client got orally 32 film-coated tablets daily after meals, during the 12-week treatment period. At the end of every month, individuals' sexual function, including ED, was evaluated by International Index of Erectile Function (IIEF) Survey and International Efficacy Question (GEQ).

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The primary outcome measure was the modification in IIEF score after 12 weeks of treatment. Complete randomization (random sorting utilizing optimum allowable% deviation) with an equal variety of clients in each series was utilized. This randomization algorithm has the restriction that unequal treatment allowance is not permitted; that is, all groups must have the same target sample size.

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All outcome assessors were likewise blinded to group allocation. 86 clients in each group completed the research study. The IIEF score enhanced significantly in the TT group compared with the placebo group (