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The main goals were to compare the efficacy of extracts of the plant Tribulus terrestris (TT; marketed as Tribestan), in comparison with placebo, for the treatment of guys with erectile dysfunction (ED) and with or without hypoactive libido disorder (HSDD), as well as to keep an eye on the safety profile of the drug.

Stage IV, potential, randomized, double-blind, placebo-controlled medical trial in parallel groups. This study consisted of 180 males aged between 18 and 65 years with moderate or moderate ED and with or without HSDD: 90 were randomized to TT and 90 to placebo. Clients with ED and hypertension, diabetes mellitus, and metabolic syndrome were included in the study.

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Each Tribestan film-coated tablet includes the active substance Tribulus terrestris, herba extractum siccum (35-45:1) 250mg which is standardized to furostanol saponins (not less than 112. 5mg). tribulus tribestan got orally 32 film-coated tablets daily after meals, during the 12-week treatment period. At the end of monthly, individuals' sexual function, consisting of ED, was assessed by International Index of Erectile Function (IIEF) Survey and International Efficacy Concern (GEQ).

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The main result step was the modification in IIEF score after 12 weeks of treatment. Total randomization (random sorting utilizing optimum allowable% deviation) with an equivalent variety of clients in each series was utilized. This randomization algorithm has the restriction that unequal treatment allocation is not permitted; that is, all groups should have the very same target sample size.

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All result assessors were also blinded to group allocation. 86 patients in each group completed the research study. The IIEF score improved significantly in the TT group compared with the placebo group (