ADHD Medications - What Are the Side Effects?
Many people suffering from ADHD are medicated. It can improve symptoms but can also cause adverse effects. If you experience any side effects, talk to your GP about them.
Stimulants are the most commonly prescribed kind of prescription medication that healthcare providers prescribe for ADHD. These medications boost the levels of brain chemicals, also known as neurotransmitters that regulate the attention span and behavior.
Methylphenidate
Methylphenidate is a first-choice stimulant used to treat ADHD in adults and children. It works by increasing the activity in brain regions that regulate behavior and attention. Methylphenidate can also be used to treat other conditions, such as the condition known as narcolepsy. It can aid people suffering from the condition to stay alert and improve their ability focus and pay attention.
This medication has a high abuse potential and is classified as a Schedule II drug in the US Drug Enforcement Agency. It is recommended to take this medication exactly as prescribed to lower the risk of abuse and the adverse effects. Methylphenidate can trigger psychotic symptoms in certain people. It can also cause worse the behavior and tics of patients suffering from Tourette syndrome or bipolar disorder. People with these conditions should consult their doctor prior to starting this medication.
It is important to inform your doctor if you have any other health issues or are allergic to any foods or dyes (such as tartrazine, a yellow dye found in some processed foods and some medications and Adhansia XR). Methylphenidate may interact with certain drugs, including opioid medicines antidepressants and monoamine oxidase inhibitors such as isocarboxazid (Marplan) Linezolid (Zyvox) Methylene blue, the phenelzine (Nardil) and rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar) or tranylcypromine (Parnate).
It's also important to stay clear of alcohol and other stimulant drugs when taking methylphenidate. These medications can affect your heart rate and blood pressure. The methylphenidate tablets that are immediate-release (Ritalin) and the oral disintegrating capsule that acts long-term and chewable tablets (Quillichew-ER and Cotempla-XR-ODT), and the chewable tablets that have a long-acting action (Quillichew-ER and Cotempla-XR-ODT), contain phenylalanine. It can be a risk if a genetic condition known as phenylketonuria exists.
Bupropion
Bupropion, an antidepressant medication is a brain stimulant and improves mood. It also reduces symptoms of ADHD. It can also be used to treat depression and seasonal depression (SAD) which can occur in the winter months of fall and winter. It can also be used to aid people in quitting smoking by reducing the craving for nicotine and withdrawal symptoms.
Bupropion has been proven to reduce ADHD symptoms in adults in several studies. The pooled fixed effect RR for week-6 improvement (using an increase in clinical significance of 30% or greater on the CGI) is 1.14 (95%CI 0.95-1.37). For overall response, this equates to 52 percent of the bupropion group and 37% of the placebo group.
Bupropion could cause serious and sometimes life-threatening interactions with several different medications, including sedatives, antidepressants, and blood pressure drugs. It can also increase seizure risk in people who have a history of high blood pressure or seizures. It is not recommended in certain medical conditions and women who are pregnant or nursing are not advised to take it. Bupropion is available in the form of brand-name drugs Wellbutrin SR and Wellbutrin XL. It is also available in the form of Zyban, Budeprion SR. Aplenzin and Forfivo XL. It is also available in generic form.
Tricyclic antidepressants
Tricyclic Antidepressants, also known as TCAs are a type of drugs that function by altering brain chemicals. They were among the first antidepressants developed. Although they are not utilized as a primary treatment for depression anymore, they may still be effective for some people. They work by inhibiting the reuptake process of dopamine, serotonin and noradrenaline by increasing their presence in neurons. They are also helpful in relieving a number of other conditions, including pain syndromes and enuresis such as fibromyalgia, Phantom limb syndrome.
TCAs are effective for ADHD symptoms, whether they are prescribed alone or with stimulants. They can reduce the severity of ADHD symptoms and decrease depression, anxiety and impulsivity. Additionally, they can help manage tics, which are repetitive, uncontrollable movements or sounds like clearing the throat or blinking.
TCAs may cause adverse effects, such as sedation and dry mouth, and can increase the risk of cardiovascular issues. These drugs can interact with other medications, including anticholinergics, and should be avoided in pregnant women. They are also known to be teratogenic in animals and can cross the placenta. Speak to your doctor if concerned. There are antidepressants that are more recent that are less likely of side effects.
Selective serotonin Reuptake inhibitors (SSRIs)
SSRIs are antidepressants that hinder serotonin reuptake by neuronal cells and increase the amount of available serotonin for signaling. They also decrease anxiety and reduce impulsive behaviors. They are often used as adhd medication since they can improve symptoms in certain people and may be beneficial in conjunction with other medications. Examples of SSRIs are fluoxetine, sertraline, paroxetine and citalopram. They exhibit linear pharmacokinetics and have a lower clearance from the human body. However, they are extensively metabolized by CYP450 enzymes in the liver. This causes variable blood concentrations.
They are also prescribed to treat various disorders, including major depressive disorder, bulimia nervosa, generalized anxiety disorder, panic disorder, and posttraumatic stress disorder (PTSD). The SSRIs fluoxetine, escitalopram and sertraline may help to reduce PTSD fundamental symptoms. They aren't effective in treating other PTSD symptoms.
The SSRIs may cause a rare side effect of sexual dysfunction. It is important to discuss this with your doctor if you are thinking of taking one of these medications. It is normal for people to to try several different types of ADHD medications before they discover the one that is most effective for them. There are always new medications being developed and studied. It is important to tell your healthcare provider about all medications you take.
Selective norepinephrine Reuptake inhibitors (SNRIs).
If stimulant drugs don't help adults suffering from ADHD doctors prescribe a selective norepinephrine reuptake inhibit (SNRI). These drugs increase the levels of two brain chemicals, serotonin and norepinephrine. They also improve mood, reduce depression and anxiety.
SNRIs have similar side effects to TCAs but are safer. They are used to treat numerous conditions, including anxiety disorders and chronic pain such as fibromyalgia and nerve pain. Sometimes, they are used to treat depression, too. SNRIs are duloxetine, (Cymbalta) and venlafaxine (Effexor).
These medications inhibit the reabsorption of norepinephrine in the brain which is a normal process after neurotransmission. This causes a greater than normal the phasic release of norepinephrine. The increase in norepinephrine helps improve mood and concentration.
The SNRIs haven't been approved by the FDA for treating ADHD however, certain doctors prescribe them as an alternative stimulant. They are typically taken as pills. However, they are also available in liquid form or as patches. The FDA approved an oral SNRI called viloxazine, or Qelbree for treating ADHD in adolescents and children in April 2021. It is not a controlled substance because it does not have the potential of being misused.
Serotonin-norepinephrine reuptake inhibitors (SNRIs)
SNRIs are antidepressants that alter the levels of norepinephrine as well as serotonin in the brain. They are used for anxiety and depression, but also aid in the management of ADHD symptoms. Several studies have shown that SNRI medications, including duloxetine and venlafaxine can significantly reduce the score of different ADHD tests. However, SNRIs can increase a person's blood pressure and could interact with certain drugs. Therefore, it is essential to consult with a physician prior to taking these drugs. Additionally, improperly handled medication can harm both people and animals. Therefore, it is essential to follow the proper disposal instructions.
SSRIs or SNRIs are not been approved by the FDA for treating ADHD However, doctors may prescribe them off-label. They are effective, safe and have less side effects than stimulants. Talk to your doctor and discuss your child's symptoms.
SNRIs can raise the body's level of serotonin and norepinephrine however they aren't suitable for everyone. For instance pregnant women or breastfeeding should not take SNRIs, because they can be passed into breast milk. People with high blood pressure or liver problems should not take these medications, either, since they could increase the risk of developing cardiovascular problems.
Selective dopamine reuptake inhibitors (DARPIs)
Many people with ADHD discover that medication can help them improve their focus and concentration. They might also experience less impulse-driven behaviors. The medication is typically combined with behavioral therapy and training, which help people manage their symptoms. It takes time to identify the appropriate dosage and medication for each person. In this process, doctors monitor physical reactions to find the right balance of benefits and side effects.
Stimulant medications, like methylphenidate can increase the activity of a certain brain chemical that control memory and concentration. While they are generally effective and safe for most people, they can also cause serious side effects, such as decreased appetite and difficulty sleeping. These side effects usually subside within a few days, as your body gets used to the medication.
Children and adults can also use non-stimulant drugs. They can take longer to work however they can help improve the ability to control impulses and concentration. These include alpha-2-adrenergic agonists (atomoxetine and viloxazine), as well as guanfacine.
Antidepressants can also help treat ADHD. They can increase norepinephrine which is a neurotransmitter within the brain that helps with mood swings and depression. Bupropion is an example an antidepressant used for ADHD.
adhd medications for adults was originally prescribed "off-label" for ADHD but the drug companies eventually came up with extended-release versions and the FDA approved it as a treatment option for this disorder.