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Rick Stewart didn't learn about the laburnum trees growing in Bulgaria and their potential to produce a drug for giving up cigarette smoking back when he was the primary executive of the pharmaceutical business Amarin. He was too deep inside the drug industry, a location often criticized for its short-sighted concentrate on revenues.

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Mediabakery - Photo by Science Photo Library - "Cytisine (baptitoxine, sophorine) smoking cessation drug moleculeStylized skeletal formula (chemical structure)Atoms are shown as color-coded circles: hydrogen (hidden), carbon (grey), nitrogen (blue),

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Only then could he spot the opportunity in those yellow-flowering trees. Now, with the assistance of the National Institutes of Health, Stewart is trying to introduce the laburnum-derived drug to the U.S. market. The tablet works by interrupting tobacco cravings, just like Pfizer's top-selling Chantix, however potentially without that drug's high-profile side impacts and at a much lower price.

Today, scientists are excited about what might be the very first brand-new treatment for cigarette smoking cessation to emerge in years. "We need this," stated David Shurtleff, deputy director of the NIH Center for Complementary and Integrative Health, describing why his company is helping to get the drug approved. However laburnum's promise is not brand-new.

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From left, Ronald Martell, Rick Stewart and Anthony Clarke of Extab. cytisine for sale desires to rebrand the smoking-cessation drug Tabex as Extab for sale in Western European and U.S. markets. (Tom Pilston) In 2007, Stewart had staked his task as the head of Amarin on a different drug. Miraxion was for treating Huntington's Illness, and early on it showed signs of enhancing symptoms of the neurological disorder.

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Financiers in Amarin, a $240 million business based in New Jersey, were stunned. The business's stock fell 80 percent. Stewart ran out a task. "The CEO always falls on his sword," Stewart, 56, states now. But Miraxion did appear to assist patients with Huntington's it simply took longer than the 6 months set aside during the scientific trials.

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This led Stewart and Anthony Clarke, who also lost his task after running the trials for Amarin, to question what other misinterpreted drugs were out there. They went on a hunt. "These drugs are uncared for or undesirable. They need tender loving care," Stewart states. "And pharma, for whatever factor, can't be bothered with them." They set up a tiny business outside London called Ricanto a mash-up of their very first names.