Anti-Cancer Influence Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast

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Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant found in the treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to research the results of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcomes indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (with the exception of total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data demonstrate that using methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application within the nutraceutical and/or pharmaceutical industries.




Drying methods, solvents and extraction methods greatly get a new phytochemical compounds and biological activity from plant materials. The aims on this study would determine the consequences of numerous drying methods, various solvents and extraction methods on the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root from Vietnam. The final results established that microwave drying was a highly effective method in elimination of water regarding shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity from your P. trimera root while methanol and microwave-assisted extraction were the top solvent and means for greatest extraction from the phytochemical compounds and antioxidant capacity from your P. trimera root. The findings using this study allow retaining the greatest numbers of phytochemical compounds and antioxidant capacity from the P. trimera root for potential application inside the nutraceutical industry.


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